BDBM6477 4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonitrile 1::4-[(4-chloro-5-methoxy-2-methylphenyl)amino]-7,8-dimethoxybenzo[g]quinoline-3-carbonitrile::CHEMBL335025

SMILES COc1cc(Nc2c(cnc3cc4cc(OC)c(OC)cc4cc23)C#N)c(C)cc1Cl

InChI Key InChIKey=YZQUCHVNBPVHAO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 6477   

LigandPNGBDBM6477(CHEMBL335025 | 4-[(4-chloro-5-methoxy-2-methylphen...)
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2005
Entry Details Article
PubMed
LigandPNGBDBM6477(CHEMBL335025 | 4-[(4-chloro-5-methoxy-2-methylphen...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Src protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM6477(CHEMBL335025 | 4-[(4-chloro-5-methoxy-2-methylphen...)
Affinity DataIC50: 210nMAssay Description:Inhibition of Src-transformed fibroblast cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed