BDBM647344 US20240025892, Example 51
SMILES CCc1nnc(o1)-c1c(OC)cc(cc1OC)-c1cnc2cc(ccn12)-c1cnn(C)c1
InChI Key InChIKey=VOYZWDQJVPQGCO-UHFFFAOYSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 647344
Affinity DataIC50: 0.412nMAssay Description:Assays were performed in base reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL BSA, 0.1 mM Na3VO4, 2 mM DTT, 1...More data for this Ligand-Target Pair
Affinity DataIC50: 1.18nMAssay Description:Assays were performed in base reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL BSA, 0.1 mM Na3VO4, 2 mM DTT, 1...More data for this Ligand-Target Pair
Affinity DataIC50: 6.49nMAssay Description:Assays were performed in base reaction buffer (20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL BSA, 0.1 mM Na3VO4, 2 mM DTT, 1...More data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of Nano-Luc fused full length recombinant SIK1 (unknown origin) transfected in HEK293 cells using AMARAASAAALARRR as substrate incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Nano-Luc fused full length recombinant SIK2 (unknown origin) transfected in HEK293 cells using AMARAASAAALARRR as substrate incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Nano-Luc fused full length recombinant SIK3 (unknown origin) transfected in HEK293 cells using AMARAASAAALARRR as substrate incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant PDGFRalpha by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant CSK by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant TNIK by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant TBK1 by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant IKKepsilon by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant ABL1 by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of SIK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of SIK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair