BDBM645107 US20240010684, Ex. No 84

SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2C[C@@H]3CCCC[C@@H]3N2C(=O)[C@@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@@H]2CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)NCCCCC(=O)NC(=O)N[C@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N2)C(N)=O

InChI Key InChIKey=HHELQWVBSDJYNA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645107   

TargetMannan-binding lectin serine protease 1(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645107(US20240010684, Ex. No 84)
Affinity DataIC50: 15nMAssay Description:Recombinant human MASP1 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645107(US20240010684, Ex. No 84)
Affinity DataIC50: 87nMAssay Description:Recombinant human MASP2 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In DepthDetails
US Patent