BDBM645063 US20240010684, Ex. No 39

SMILES CC[C@H](C)[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H]2NC(=O)[C@@H](NC(=O)[C@@H]3CCCN3C(=O)[C@@H]3CCCN3C(=O)[C@H](CC(C)(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CSSC2(C)C)NC1=O)[C@@H](C)CC)[C@@H](C)CC

InChI Key InChIKey=ICVOVESZOWJGKB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 645063   

TargetMannan-binding lectin serine protease 1(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645063(US20240010684, Ex. No 39)
Affinity DataIC50: 6nMAssay Description:Recombinant human MASP1 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645063(US20240010684, Ex. No 39)
Affinity DataIC50: 75nMAssay Description:Recombinant human MASP2 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMannan-binding lectin serine protease 1(Rat)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645063(US20240010684, Ex. No 39)
Affinity DataIC50: 44nMAssay Description:Recombinant rat MASP1 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM G...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMannan-binding lectin serine protease 2(Rat)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645063(US20240010684, Ex. No 39)
Affinity DataIC50: 8nMAssay Description:Recombinant rat MASP2 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM G...More data for this Ligand-Target Pair
In DepthDetails
US Patent