BDBM645042 US20240010684, Ex. No 18

SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)NC(=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC1=O)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C=O

InChI Key InChIKey=MZNVGSFTUFDCTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645042   

TargetMannan-binding lectin serine protease 1(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645042(US20240010684, Ex. No 18)
Affinity DataIC50: 50nMAssay Description:Recombinant human MASP1 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
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TargetMannan-binding lectin serine protease 2(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645042(US20240010684, Ex. No 18)
Affinity DataIC50: 15nMAssay Description:Recombinant human MASP2 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent