BDBM644948 US20240009175, Compound 55::[1,5-dimethy-6-(1H-1,2,3,4-tetrazol-5- yl)-1H-imidazo[4,5-b]pyridin-2-yl]bis(2- fluorophenyl)methanol

SMILES Cc1nc2nc(n(C)c2cc1-c1nnn[nH]1)C(O)(c1ccccc1F)c1ccccc1F

InChI Key InChIKey=COJHYALGAXUAMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 644948   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM644948(US20240009175, Compound 55 | [1,5-dimethy-6-(1H-1,...)
Affinity DataIC50: 1nMAssay Description:The assay was performed in Perkin Elmer 384 well white Proxiplates in a total volume of 8 μl. 1 nM (fc)C-term myc tagged ACSS2 (human, recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent