BDBM642738 US20230416271, Compound I.7

SMILES CC(C)c1noc2c(Cl)cc3cnc(NC4CCN(CC4)S(C)(=O)=O)nc3c12

InChI Key InChIKey=LXWKFZODCMNRLB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 642738   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM642738(US20230416271, Compound I.7)
Affinity DataIC50: 8nMAssay Description:Assay of Kinase Activity The inhibitory effect of compounds against the kinase CDK4/cyclin D3 was detected by Caliper Mobility Shift Assay method. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2024
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM642738(US20230416271, Compound I.7)
Affinity DataIC50: 7nMAssay Description:Assay of Kinase Activity The inhibitory effect of compounds against the kinase CDK4/cyclin D3 was detected by Caliper Mobility Shift Assay method. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2024
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM642738(US20230416271, Compound I.7)
Affinity DataIC50: 3nMAssay Description:Assay of Kinase Activity The inhibitory effect of compounds against the kinase CDK4/cyclin D3 was detected by Caliper Mobility Shift Assay method. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2024
Entry Details
Go to US Patent