BDBM6419 N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]amino]-3-pyridinyl]-2-pyrazinamine::N-(3-chlorophenyl)-6-(5-{[3-(pyridin-3-yl)propyl]amino}pyridin-3-yl)pyrazin-2-amine::Pyrazine-Pyridine Biheteroaryl 56

SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCc3cccnc3)c2)c1

InChI Key InChIKey=IRNVMUQZQDLZAK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 6419   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-chlorophenyl)-6-(5-{[3-(pyridin-3-yl)propyl]a...)
Affinity DataIC50: 1.00E+4nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-chlorophenyl)-6-(5-{[3-(pyridin-3-yl)propyl]a...)
Affinity DataIC50: 76nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-chlorophenyl)-6-(5-{[3-(pyridin-3-yl)propyl]a...)
Affinity DataIC50: 876nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-chlorophenyl)-6-(5-{[3-(pyridin-3-yl)propyl]a...)
Affinity DataIC50: 318nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-chlorophenyl)-6-(5-{[3-(pyridin-3-yl)propyl]a...)
Affinity DataIC50: 293nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-chlorophenyl)-6-(5-{[3-(pyridin-3-yl)propyl]a...)
Affinity DataIC50: 1.00E+4nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed