BDBM639312 (R and S)-N-(4,4-difluoro-3- piperidyl)-7-[2-(2,2,2- trifluoroethoxy)phenyl] benzofuran-2-carboxamide::US20230391758, Compound 14

SMILES FC(F)(F)COc1ccccc1-c1cccc2cc(oc12)C(=O)NC1CNCCC1(F)F

InChI Key InChIKey=KOQKPHSJXVASPP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639312   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639312((R and S)-N-(4,4-difluoro-3- piperidyl)-7-[2-(2,2,...)
Affinity DataEC50:  0.480nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
In DepthDetails
US Patent