BDBM6391 (3-Chloro-phenyl)-{6-[5-(3-pyridin-4-yl-propylamino)-pyridin-3-yl]-pyrazin-2-yl}-amine::N-(3-chlorophenyl)-6-(5-{[3-(pyridin-4-yl)propyl]amino}pyridin-3-yl)pyrazin-2-amine::Pyrazine-Pyridine Biheteroaryl 20

SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCc3ccncc3)c2)c1

InChI Key InChIKey=WYCDDSZFBQZASO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6391   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6391(N-(3-chlorophenyl)-6-(5-{[3-(pyridin-4-yl)propyl]a...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6391(N-(3-chlorophenyl)-6-(5-{[3-(pyridin-4-yl)propyl]a...)
Affinity DataIC50: 76nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed