BDBM637547 (3RS,4RS)-4-(3-amino-6- cyclopropylpyrazolo[3,4- b]pyridine-1-carbonyl)-3- methylpiperidin-2-one::US20230382911, Example 59

SMILES C[C@@H]1[C@@H](CCNC1=O)C(=O)n1nc(N)c2ccc(nc12)C1CC1

InChI Key InChIKey=VXYBQKHOZVOXPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637547   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM637547((3RS,4RS)-4-(3-amino-6- cyclopropylpyrazolo[3,4- b...)
Affinity DataIC50: 33nMAssay Description:Recombinant human Mat2a (12.5 nM) and serial diluted compounds in DMSO (range of concentrations from 10 μM to 508 μM) or controls (DMSO) ar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
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