BDBM637540 (3-amino-6-cyclopropyl-1H- pyrazolo[3,4-b]pyridin-1- yl)((2RS,3SR)-3- methyltetrahydrofuran-2- yl)methanone::US20230382911, Example 52::US20230382911, Example 65

SMILES C[C@H]1OCC[C@H]1C(=O)n1nc(N)c2ccc(nc12)C1CC1

InChI Key InChIKey=WRESKPJSCZPEBU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 637540   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM637540(US20230382911, Example 52 | (3-amino-6-cyclopropyl...)
Affinity DataIC50: 35nMAssay Description:Recombinant human Mat2a (12.5 nM) and serial diluted compounds in DMSO (range of concentrations from 10 μM to 508 μM) or controls (DMSO) ar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent

TargetS-adenosylmethionine synthase isoform type-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM637540(US20230382911, Example 52 | (3-amino-6-cyclopropyl...)
Affinity DataIC50: 36nMAssay Description:Recombinant human Mat2a (12.5 nM) and serial diluted compounds in DMSO (range of concentrations from 10 μM to 508 μM) or controls (DMSO) ar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent