BDBM637531 (3-amino-6-((1rs,2RS,3SR)-2,3- dimethylcyclopropyl)-1H- pyrazolo[3,4-b]pyridin-1-yl)(o- tolyl)methanone::US20230382911, Example 43

SMILES C[C@H]1[C@@H](C)[C@@H]1c1ccc2c(N)nn(C(=O)c3ccccc3C)c2n1

InChI Key InChIKey=KJRRTSQQEWQKGT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637531   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM637531((3-amino-6-((1rs,2RS,3SR)-2,3- dimethylcyclopropyl...)
Affinity DataIC50: 35nMAssay Description:Recombinant human Mat2a (12.5 nM) and serial diluted compounds in DMSO (range of concentrations from 10 μM to 508 μM) or controls (DMSO) ar...More data for this Ligand-Target Pair
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Date in BDB:
1/19/2024
Entry Details
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