BDBM637514 (3-amino-6-(trifluoromethyl-1H- pyrazolo[3,4-b]pyridin-1-yl)(2- methoxyphenyl)methanone::US20230382911, Example 26

SMILES COc1ccccc1C(=O)n1nc(N)c2ccc(nc12)C(F)(F)F

InChI Key InChIKey=NAHIINRXDJHZCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637514   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM637514((3-amino-6-(trifluoromethyl-1H- pyrazolo[3,4-b]pyr...)
Affinity DataIC50: 120nMAssay Description:Recombinant human Mat2a (12.5 nM) and serial diluted compounds in DMSO (range of concentrations from 10 μM to 508 μM) or controls (DMSO) ar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
Go to US Patent