BDBM636704 US20230365627, Compound 1028

SMILES CCCC[C@@H]1N(C)C(=O)[C@H](CCCC)N(C)C(=O)[C@@H]2Cc3cn(CC(=O)OB(O)c4ccc(CNC[C@@H]5NC(=O)[C@@H]6CCCN6C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc6ccc(OB(O)c7ccc(CNCC[C@H](NC(=O)[C@H](Cc8c[nH]c9ccccc89)NC(=O)[C@@H]8C[C@@H](O)CN8C(=O)[C@H](CC(C)C)NC5=O)C(=O)N2)c(F)c7)cc6)NC(=O)CSC[C@H](NC(=O)[C@H](CC(C)C)NC1=O)C(=O)NCC(N)=O)c(F)c4)c1ccccc31

InChI Key InChIKey=AIQOCHHGBVRGCU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636704   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM636704(US20230365627, Compound 1028)
Affinity DataIC50: 4.60nMAssay Description:Homogenous Time-Resolved Fluorescence (HTRF) Binding Assay. The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2024
Entry Details
Go to US Patent