BDBM636690 US20230365627, Compound 1014::US20230365627, Compound 1027

SMILES CCCC[C@@H]1N(C)C(=O)[C@H](CCCC)N(C)C(=O)[C@H](Cc2cn(CC(O)=O)c3ccccc23)NC(=O)[C@H](CCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CNCc2cc(C)c(B(O)O)c(C)c2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](CC(C)C)NC1=O)C(=O)NCC(N)=O

InChI Key InChIKey=YPYBLGXDAALPRQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 636690   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM636690(US20230365627, Compound 1014 | US20230365627, Comp...)
Affinity DataIC50: 8.20nMAssay Description:Homogenous Time-Resolved Fluorescence (HTRF) Binding Assay. The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2024
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM636690(US20230365627, Compound 1014 | US20230365627, Comp...)
Affinity DataIC50: 3.80nMAssay Description:Homogenous Time-Resolved Fluorescence (HTRF) Binding Assay. The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2024
Entry Details
Go to US Patent