BDBM636687 US20230365627, Compound 1011

SMILES CCCC[C@@H]1N(C)C(=O)[C@H](CCCC)N(C)C(=O)[C@@H]2Cc3cn(CC(=O)OB(O)c4cc(CNC[C@H](NC(=O)[C@@H]5CCCN5C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc5ccc(O)cc5)NC(=O)CSC[C@H](NC(=O)[C@H](CC(C)C)NC1=O)C(=O)NCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](Cc1c[nH]c5ccccc15)C(=O)N[C@@H](CCN)C(=O)N2)ccc4Cl)c1ccccc31

InChI Key InChIKey=LRHVMCUFQSVTEC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636687   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM636687(US20230365627, Compound 1011)
Affinity DataIC50: 6.40nMAssay Description:Homogenous Time-Resolved Fluorescence (HTRF) Binding Assay. The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2024
Entry Details
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