BDBM636680 US20230365627, Compound 1004

SMILES CCCC[C@@H]1N(C)C(=O)[C@H](CCCC)N(C)C(=O)[C@H](Cc2cn(CC(O)=O)c3ccccc23)NC(=O)[C@@H]2CCNCc3ccc(cc3)B3OB(O3)c3ccc(CNC[C@H](NC(=O)[C@@H]4CCCN4C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc4ccc(O)cc4)NC(=O)CSC[C@H](NC(=O)[C@H](CC(C)C)NC1=O)C(=O)NCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](Cc1c[nH]c4ccccc14)C(=O)N2)cc3

InChI Key InChIKey=PCZQFBQXCBIKGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636680   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM636680(US20230365627, Compound 1004)
Affinity DataIC50: 6.30nMAssay Description:Homogenous Time-Resolved Fluorescence (HTRF) Binding Assay. The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2024
Entry Details
Go to US Patent