BDBM6361 8-Cyclopentyl-5-methyl-2-(4-piperidin-1-yl-phenylamino)-8H-pyrido[2,3-d]pyrimidin-7-one::8-cyclopentyl-5-methyl-2-{[4-(piperidin-1-yl)phenyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::Pyrido[2,3-d]pyrimidin-7-one 8

SMILES Cc1cc(=O)n(C2CCCC2)c2nc(Nc3ccc(cc3)N3CCCCC3)ncc12

InChI Key InChIKey=RMNWLVFFWRBNQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6361   

LigandPNGBDBM6361(8-Cyclopentyl-5-methyl-2-(4-piperidin-1-yl-phenyla...)
Affinity DataIC50: 180nMpH: 7.4 T: 2°CAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2005
Entry Details Article
PubMed
LigandPNGBDBM6361(8-Cyclopentyl-5-methyl-2-(4-piperidin-1-yl-phenyla...)
Affinity DataIC50: 5.00E+3nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2005
Entry Details Article
PubMed