BDBM630400 US11802110, Compound 4.20

SMILES CC(C)CC(N)C(=O)NS(=O)c1cccc(OC(F)(F)F)c1

InChI Key InChIKey=BYTXNNIKXMVSKT-UHFFFAOYSA-N

Data  1 Kd  1 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 630400   

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM630400(US11802110, Compound 4.20)
Affinity DataKd:  1.39nMAssay Description:ITC studies were carried out using a Microcal ITC200 instrument (GE Healthcare). Protein concentration was determined by spectrophotometry by measuri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 630400   

CellLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
SyringePNGBDBM630400(US11802110, Compound 4.20)
ITC DataΔG°: -12.1kcal/mole −TΔS°: 0kcal/mole ΔH°: -11.6kcal/mole logk: 4.32E+6
pH: 7.5 T: 125.01°C 
In DepthDetails
US Patent