BDBM625316 N-{4-[3-(4-fluorophenyl)-5-methyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridin-2-yl}-2-[4-(piperazine-1-carbonyl)phenyl]acetamide::US20230322767, Example 144

SMILES CN1CCc2[nH]c(c(c2C1=O)-c1ccc(F)cc1)-c1ccnc(NC(=O)Cc2ccc(cc2)C(=O)N2CCNCC2)c1

InChI Key InChIKey=FUBHPUWOZAXCKP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 625316   

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625316(US20230322767, Example 144 | N-{4-[3-(4-fluorophen...)
Affinity DataIC50: 2nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetCasein kinase I isoform delta(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625316(US20230322767, Example 144 | N-{4-[3-(4-fluorophen...)
Affinity DataIC50: 3nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1D, expressed by baculovirus infected insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetEpidermal growth factor receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625316(US20230322767, Example 144 | N-{4-[3-(4-fluorophen...)
Affinity DataIC50: 3.62E+3nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent