BDBM625257 2-(4-fluorophenyl)-N-{4-[3-(3-fluorophenyl)-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridin-2-yl}acetamide::US20230322767, Example 85

SMILES CC1(C)Cc2[nH]c(c(c2C(=O)N1)-c1cccc(F)c1)-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1

InChI Key InChIKey=IANCPMFLRNSETO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 625257   

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625257(US20230322767, Example 85 | 2-(4-fluorophenyl)-N-{...)
Affinity DataIC50: 1.90nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetCasein kinase I isoform delta(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625257(US20230322767, Example 85 | 2-(4-fluorophenyl)-N-{...)
Affinity DataIC50: 3.90nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1D, expressed by baculovirus infected insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625257(US20230322767, Example 85 | 2-(4-fluorophenyl)-N-{...)
Affinity DataIC50: 5.71E+3nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent