BDBM625247 2-(4-fluorophenyl)-N-[4-(4-oxo-3-phenyl-4,5-dihydro-1H-pyrrolo[3,2-c]pyridin-2-yl)pyridin-2-yl]acetamide::US20230322767, Example 73

SMILES Fc1ccc(CC(=O)Nc2cc(ccn2)-c2[nH]c3cc[nH]c(=O)c3c2-c2ccccc2)cc1

InChI Key InChIKey=RTZRQMLMSQRVKR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 625247   

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625247(US20230322767, Example 73 | 2-(4-fluorophenyl)-N-[...)
Affinity DataIC50: 1.90nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetCasein kinase I isoform delta(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625247(US20230322767, Example 73 | 2-(4-fluorophenyl)-N-[...)
Affinity DataIC50: 5.40nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1D, expressed by baculovirus infected insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
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TargetEpidermal growth factor receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625247(US20230322767, Example 73 | 2-(4-fluorophenyl)-N-[...)
Affinity DataIC50: 2.00E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent