BDBM624995 US20230322747, Compound 17

SMILES FC(F)c1nnc(o1)-c1ccc(COc2cccnc2)nc1

InChI Key InChIKey=XHZJQIJAXUULAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624995   

TargetHistone deacetylase 6(Human)
Eikonizo Therapeutics

US Patent
LigandPNGBDBM624995(US20230322747, Compound 17)
Affinity DataIC50: 50nMAssay Description:The biochemical HDAC6 assay was performed using fluorescence detection (Fluor-De-Lys assay). In this assay, deacetylation of the Lysine residue in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Eikonizo Therapeutics

US Patent
LigandPNGBDBM624995(US20230322747, Compound 17)
Affinity DataIC50: 5.50E+4nMAssay Description:HDAC reactions were assembled in 384 well plates (Greiner) in a total volume of 20 μL as follows: HDAC proteins (and their regulatory subunit, i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent