BDBM624934 US20230322715, Compound TR-ALKBH5-32

SMILES FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCc1ccccn1

InChI Key InChIKey=GBIIJEKUQUHJQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624934   

TargetRNA demethylase ALKBH5(Human)
University of California

US Patent
LigandPNGBDBM624934(US20230322715, Compound TR-ALKBH5-32)
Affinity DataIC50: 2.20E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of California

US Patent
LigandPNGBDBM624934(US20230322715, Compound TR-ALKBH5-32)
Affinity DataIC50: 4.00E+4nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent