BDBM624880 US20230322715, Compound TR-FTO-48

SMILES FC1CCN(C1)C1(CNCC2CCC(O2)c2ccccc2)COC1

InChI Key InChIKey=QURQKASPEKVJFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624880   

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of California

US Patent
LigandPNGBDBM624880(US20230322715, Compound TR-FTO-48)
Affinity DataIC50: 2.00E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetRNA demethylase ALKBH5(Human)
University of California

US Patent
LigandPNGBDBM624880(US20230322715, Compound TR-FTO-48)
Affinity DataIC50: 2.60E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent