BDBM624874 US20230322715, Compound TR-FTO-39

SMILES COc1ccc2nc(Cl)c(CNCC3(COC3)N3CCCC3)cc2c1

InChI Key InChIKey=JRYWWHXGBCTGCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624874   

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of California

US Patent
LigandPNGBDBM624874(US20230322715, Compound TR-FTO-39)
Affinity DataIC50: 1.70E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetRNA demethylase ALKBH5(Human)
University of California

US Patent
LigandPNGBDBM624874(US20230322715, Compound TR-FTO-39)
Affinity DataIC50: 920nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent