BDBM624871 US20230322715, Compound TR-FTO-35

SMILES C(NCC1(COC1)N1CCCC1)C1CCC(O1)c1ccccc1

InChI Key InChIKey=KRGDBFSJYYMNMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624871   

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM624871(US20230322715, Compound TR-FTO-35)
Affinity DataIC50: 70nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM624871(US20230322715, Compound TR-FTO-35)
Affinity DataIC50: 5.50E+4nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent