BDBM624773 US11780851, Example 43

SMILES Cc1c2Nc3ncc4c(Cl)nn(CCCOc2nn1[C@@H]1CCOC(C)(C)C1)c4n3

InChI Key InChIKey=QHIPUDMIERKTCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624773   

LigandPNGBDBM624773(US11780851, Example 43)
Affinity DataIC50: 5.30nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM624773(US11780851, Example 43)
Affinity DataIC50: 17nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent