BDBM624752 US11780851, Example 22

SMILES C[C@@H]1COCC[C@H]1n1nc2OCCCn3nc(Cl)c4cnc(Nc2c1C)nc34

InChI Key InChIKey=HULLTRDAGVTWLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624752   

LigandPNGBDBM624752(US11780851, Example 22)
Affinity DataIC50: 3.5nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM624752(US11780851, Example 22)
Affinity DataIC50: 10nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent