BDBM624743 US11780851, Example 13::US11780851, Example 15

SMILES Cc1c(c(OCCCn2nc(Cl)c3cnc(Cl)nc23)nn1C1CCOCC1)[N+]([O-])=O

InChI Key InChIKey=KYZODZDUZCQGAQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 624743   

LigandPNGBDBM624743(US11780851, Example 15 | US11780851, Example 13)
Affinity DataIC50: 25nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
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LigandPNGBDBM624743(US11780851, Example 15 | US11780851, Example 13)
Affinity DataIC50: 9.60nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM624743(US11780851, Example 15 | US11780851, Example 13)
Affinity DataIC50: 2.40nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM624743(US11780851, Example 15 | US11780851, Example 13)
Affinity DataIC50: 6.80nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent