BDBM624732 US11780851, Example 2::US11780851, Example 20::US11780851, Example 35::US11780851, Example 45::US11780851, Example 46

SMILES Cc1c2Nc3ncc4c(Cl)nn(CCCOc2nn1C1CCOCC1)c4n3

InChI Key InChIKey=RPEXRSTZKDPTMZ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 624732   

LigandPNGBDBM624732(US11780851, Example 20 | US11780851, Example 35 | ...)
Affinity DataIC50: 2.40nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
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LigandPNGBDBM624732(US11780851, Example 20 | US11780851, Example 35 | ...)
Affinity DataIC50: 9.80nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM624732(US11780851, Example 20 | US11780851, Example 35 | ...)
Affinity DataIC50: 5.10nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM624732(US11780851, Example 20 | US11780851, Example 35 | ...)
Affinity DataIC50: 14nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM624732(US11780851, Example 20 | US11780851, Example 35 | ...)
Affinity DataIC50: 5.30nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM624732(US11780851, Example 20 | US11780851, Example 35 | ...)
Affinity DataIC50: 15nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM624732(US11780851, Example 20 | US11780851, Example 35 | ...)
Affinity DataIC50: 3.60nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM624732(US11780851, Example 20 | US11780851, Example 35 | ...)
Affinity DataIC50: 13nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM624732(US11780851, Example 20 | US11780851, Example 35 | ...)
Affinity DataIC50: 3.10nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM624732(US11780851, Example 20 | US11780851, Example 35 | ...)
Affinity DataIC50: 12nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
Go to US Patent