BDBM62337 Synthetic Example 4 (WO2008/071451)
SMILES CC1=C(C#N)C(C(C#N)=C(C)N1)c1cccc2[nH]ncc12
InChI Key InChIKey=KOTXGCGGLKMMDL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 62337
Affinity DataIC50: 8nMpH: 7.0 T: 2°CAssay Description:Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The N-terminally His6-tagged recombinant kinase domain of the human c-Met (amino acids 960-1390), expressed in insect cells (SF21) and purified by Ni...More data for this Ligand-Target Pair