BDBM622398 US20230312576, Compound 30

SMILES COc1cccc(c1)-c1cccc(NC(=O)N2CCC(=CC2)c2ncnc3[nH]cc(C)c23)c1

InChI Key InChIKey=ZHVBPFYLCBVTAE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 622398   

TargetLIM domain kinase 2(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622398(US20230312576, Compound 30)
Affinity DataKi:  8.15nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent

TargetLIM domain kinase 1(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622398(US20230312576, Compound 30)
Affinity DataKi:  15.2nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
Go to US Patent