BDBM621183 US20230303564, Compound 25

SMILES C[C@@H]1CCCN1c1nc(cc2cnc(NC3CCN(CC3)S(C)(=O)=O)nc12)C(F)F

InChI Key InChIKey=RDFSLQYYDUOMGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 621183   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM621183(US20230303564, Compound 25)
Affinity DataIC50: 4.02nMAssay Description:Enzymes, substrates, ATP, and inhibitors were diluted by kinase buffer in the kit. The compounds to be tested were diluted 5-fold with a multi-channe...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM621183(US20230303564, Compound 25)
Affinity DataIC50: 0.460nMAssay Description:Preparation of Kinase Buffer: The composition of the buffer: 50 mM of hydroxyethylpiperazine ethanesulfonic acid solution at pH 7.5, 1 mM of ethylene...More data for this Ligand-Target Pair
In DepthDetails
US Patent