BDBM621035 (6-((4-(2-(dimethylamino)benzothiazole-6-yl)-5-fluoropyrimidine-2-yl)amino)pyridine-3-yl)(4-ethylpiperazine-1-yl)ketone::US20230303553, Example 31

SMILES CCN1CCN(CC1)C(=O)c1ccc(Nc2ncc(F)c(n2)-c2ccc3nc(sc3c2)N(C)C)nc1

InChI Key InChIKey=AWBAKFAKVVKANT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 621035   

TargetCyclin-dependent kinase 6(Human)
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621035(US20230303553, Example 31 | (6-((4-(2-(dimethylami...)
Affinity DataIC50: 18nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621035(US20230303553, Example 31 | (6-((4-(2-(dimethylami...)
Affinity DataIC50: 9nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
In DepthDetails
US Patent