BDBM618474 US20230286978, Example 10

SMILES Fc1cnccc1-c1n[nH]c2c(cccc12)C(=O)NCc1ccc(Cl)cc1

InChI Key InChIKey=POKKNQYTCJAJQE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 618474   

TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM618474(US20230286978, Example 10)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 µL. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
In DepthDetails
US Patent