BDBM6169 1,6-naphthyridine 38::N-[3-(Benzyloxy)propyl]-N-[2-[[(tert-butylamino)carbonyl]amino]-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-7-yl]acetamide::N-[3-(benzyloxy)propyl]-N-{2-[(tert-butylcarbamoyl)amino]-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-7-yl}acetamide

SMILES COc1cc(OC)cc(c1)-c1cc2cnc(cc2nc1NC(=O)NC(C)(C)C)N(CCCOCc1ccccc1)C(C)=O

InChI Key InChIKey=ZXBIAWLOGMFTPF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6169   

TargetPlatelet-derived growth factor receptor beta(Mouse)
University of Auckland

LigandPNGBDBM6169(N-[3-(benzyloxy)propyl]-N-{2-[(tert-butylcarbamoyl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM6169(N-[3-(benzyloxy)propyl]-N-{2-[(tert-butylcarbamoyl...)
Affinity DataIC50: 1.50E+3nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandPNGBDBM6169(N-[3-(benzyloxy)propyl]-N-{2-[(tert-butylcarbamoyl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Auckland

LigandPNGBDBM6169(N-[3-(benzyloxy)propyl]-N-{2-[(tert-butylcarbamoyl...)
Affinity DataIC50: 84nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2005
Entry Details Article
PubMed