BDBM61632 5-[(E)-(tert-butylthiocarbamoylhydrazono)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylic acid methyl ester::5-[(tert-butylthiocarbamoylhydrazono)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylic acid methyl ester::5-[[[(tert-butylamino)-sulfanylidenemethyl]hydrazinylidene]methyl]-1-(2,4-difluorophenyl)-4-pyrazolecarboxylic acid methyl ester::MLS000834953::SMR000461569::cid_2745687::methyl 1-[2,4-bis(fluoranyl)phenyl]-5-[(tert-butylcarbamothioylhydrazinylidene)methyl]pyrazole-4-carboxylate::methyl 5-[(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate::methyl 5-{2-[(tert-butylamino)carbothioyl]carbohydrazonoyl}-1-(2,4-difluorophenyl)-1H-pyrazole-4-carboxylate

SMILES COC(=O)c1cnn(c1C=NNC(=S)NC(C)(C)C)-c1ccc(F)cc1F

InChI Key InChIKey=CYNLZIBKERMMOA-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 61632   

TargetG-protein coupled receptor 35(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61632(methyl 1-[2,4-bis(fluoranyl)phenyl]-5-[(tert-butyl...)
Affinity DataIC50: 500nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetG-protein coupled receptor 35(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61632(methyl 1-[2,4-bis(fluoranyl)phenyl]-5-[(tert-butyl...)
Affinity DataIC50: 160nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) Netw...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetG-protein coupled receptor 55(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61632(methyl 1-[2,4-bis(fluoranyl)phenyl]-5-[(tert-butyl...)
Affinity DataIC50: 9.08E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics(SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetG-protein coupled receptor 35(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61632(methyl 1-[2,4-bis(fluoranyl)phenyl]-5-[(tert-butyl...)
Affinity DataIC50: 1.39E+3nMAssay Description:Data Source: Dr. Mary Abood Source Affiliation: Temple University Network: NIH Molecular Libraries Probe Production Centers Network (MLPCN) Grant Pro...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetG-protein coupled receptor 35(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61632(methyl 1-[2,4-bis(fluoranyl)phenyl]-5-[(tert-butyl...)
Affinity DataIC50: 1.04E+4nMAssay Description:Antagonist activity at human GPR35 expressed in human HT29 cells after 1 hr by DMR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetG-protein coupled receptor 35(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61632(methyl 1-[2,4-bis(fluoranyl)phenyl]-5-[(tert-butyl...)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human Gal4-VP16 fused GPR35 expressed in human U2OS cells assessed as beta arrestin translocation by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetG-protein coupled receptor 35(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61632(methyl 1-[2,4-bis(fluoranyl)phenyl]-5-[(tert-butyl...)
Affinity DataIC50: 574nMAssay Description:Antagonist activity at C-terminal beta-galactosidase tagged human recombinant GPR35 expressed in CHO cells after 90 mins by beta-arrestin recruitment...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetG-protein coupled receptor 35(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61632(methyl 1-[2,4-bis(fluoranyl)phenyl]-5-[(tert-butyl...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed