BDBM616098 US20230271964, Example 1-55::US20230271964, Example 1-56

SMILES Cn1ccnc1Cn1nc2c(-c3cc(Cl)nc(CO)c3)c(nc(N)n2c1=O)-c1ccccc1

InChI Key InChIKey=RKWXSHJWRZFBGD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 616098   

TargetAdenosine receptor A2a(Human)
Astrazeneca

US Patent
LigandPNGBDBM616098(US20230271964, Example 1-55 | US20230271964, Examp...)
Affinity DataKi:  0.158nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
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TargetAdenosine receptor A2a(Human)
Astrazeneca

US Patent
LigandPNGBDBM616098(US20230271964, Example 1-55 | US20230271964, Examp...)
Affinity DataKi:  0.398nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Astrazeneca

US Patent
LigandPNGBDBM616098(US20230271964, Example 1-55 | US20230271964, Examp...)
Affinity DataKi:  5.01nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Astrazeneca

US Patent
LigandPNGBDBM616098(US20230271964, Example 1-55 | US20230271964, Examp...)
Affinity DataKi:  31.6nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent