BDBM616093 US20230271964, Example 1-50

SMILES Cc1cc(cc(CO)n1)-c1c(nc(N)n2c1nn(Cc1nccn1C)c2=O)-c1ccc(F)cc1

InChI Key InChIKey=KRGQUBGMMXPUTM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 616093   

TargetAdenosine receptor A2a(Human)
Astrazeneca

US Patent
LigandPNGBDBM616093(US20230271964, Example 1-50)
Affinity DataKi:  0.316nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
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TargetAdenosine receptor A1(Human)
Astrazeneca

US Patent
LigandPNGBDBM616093(US20230271964, Example 1-50)
Affinity DataKi:  316nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM616093(US20230271964, Example 1-50)
Affinity DataKi:  8.61E+4nMAssay Description:Receptor binding: Evaluation of the affinity of compounds for the agonist site of the human CB-1 cannabinoid receptor in transfected CHO cells determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent