BDBM615630 2-[(1S)-1-(4-{[(1R,5S,6S)-6-(5,5-dimethyl-4,5-dihydro-1,2-oxazol-3-yl)-3-azabicyclo[3.1.0]hex-3-yl]carbonyl}-1H-imidazol-1-yl)ethyl]benzonitrile::US20230271952, Example 22

SMILES C[C@@H](c1ccccc1C#N)n1cnc(c1)C(=O)N1C[C@H]2[C@@H](C1)[C@@H]2C1=NOC(C)(C)C1

InChI Key InChIKey=ZWKRPZNMZJSQNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 615630   

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615630(2-[(1S)-1-(4-{[(1R,5S,6S)-6-(5,5-dimethyl-4,5-dihy...)
Affinity DataIC50: 400nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
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Date in BDB:
10/16/2023
Entry Details
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