BDBM615124 3-[2-(4-bromophenyl)-5-methyl-1H-indol-3-yl]-N-[(3S)-2-oxopyrrolidin-3-yl]propanamide (43)::US20230271945, Compound 43

SMILES Cc1ccc2[nH]c(c(CCC(=O)N[C@H]3CCNC3=O)c2c1)-c1ccc(Br)cc1

InChI Key InChIKey=UOUKGCFYJSFPGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 615124   

TargetApolipoprotein L1(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615124(3-[2-(4-bromophenyl)-5-methyl-1H-indol-3-yl]-N-[(3...)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615124(3-[2-(4-bromophenyl)-5-methyl-1H-indol-3-yl]-N-[(3...)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent