BDBM615086 3-[5,7-difluoro-2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(3S)-2-oxopyrrolidin-3-yl]propanamide (3)::US20230271945, Compound 3

SMILES Fc1ccc(cc1)-c1[nH]c2c(F)cc(F)cc2c1CCC(=O)N[C@H]1CCNC1=O

InChI Key InChIKey=XXHTXOAUVHFTLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 615086   

TargetApolipoprotein L1(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615086(3-[5,7-difluoro-2-(4-fluorophenyl)-1H-indol-3-yl]-...)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615086(3-[5,7-difluoro-2-(4-fluorophenyl)-1H-indol-3-yl]-...)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent