BDBM610664 5-[(2R,6S)-2-methyl-6-[[4-(1,2,3,4-tetrahydroisoquinolin-7-yl)piperazin-1-yl]methyl]morpholin-4-yl]quinoline-8-carbonitrile::US11713327, Example 9

SMILES C[C@@H]1CN(C[C@H](CN2CCN(CC2)c2ccc3CCNCc3c2)O1)c1ccc(C#N)c2ncccc12

InChI Key InChIKey=MXMCOIZKLAARAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 610664   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM610664(US11713327, Example 9 | 5-[(2R,6S)-2-methyl-6-[[4-...)
Affinity DataIC50: 2.00E+4nMAssay Description:The hERG channel inhibition assay is a highly sensitive measurement that identifies compounds exhibiting hERG inhibition related to cardiotoxicity in...More data for this Ligand-Target Pair
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Date in BDB:
9/4/2023
Entry Details
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