BDBM610663 7-[(2S,6R)-2-[[4-(6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-3-yl)piperazin-1-yl]methyl]-6-methyl-morpholin-4-yl]-1,3-benzothiazole-4-carbonitrile::US11713327, Example 8

SMILES C[C@@H]1CN(C[C@H](CN2CCN(CC2)c2cnc3CNCc3c2)O1)c1ccc(C#N)c2ncsc12

InChI Key InChIKey=BSOZAOPJZOXJIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 610663   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM610663(US11713327, Example 8 | 7-[(2S,6R)-2-[[4-(6,7-dihy...)
Affinity DataIC50: 2.00E+4nMAssay Description:The hERG channel inhibition assay is a highly sensitive measurement that identifies compounds exhibiting hERG inhibition related to cardiotoxicity in...More data for this Ligand-Target Pair
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Date in BDB:
9/4/2023
Entry Details
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