BDBM6102 4-[(2-Chloro-5-methoxyphenyl)amino]-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinoline-3-carbonitrile::4-phenylamino-3-quinolinecarbonitrile 20

SMILES COc1ccc(Cl)c(Nc2c(cnc3cc(OCC4CCN(C)CC4)c(OC)cc23)C#N)c1

InChI Key InChIKey=ZPKGDYKWVKCDJQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6102   

LigandPNGBDBM6102(4-[(2-Chloro-5-methoxyphenyl)amino]-6-methoxy-7-[(...)
Affinity DataIC50: 12nMAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Wyeth Research

LigandPNGBDBM6102(4-[(2-Chloro-5-methoxyphenyl)amino]-6-methoxy-7-[(...)
Affinity DataIC50: 3.5nMAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6102(4-[(2-Chloro-5-methoxyphenyl)amino]-6-methoxy-7-[(...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM6102(4-[(2-Chloro-5-methoxyphenyl)amino]-6-methoxy-7-[(...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed