BDBM609384 US11702418, Example 5-2
SMILES CCc1nnc(NC(C)c2ccc(s2)-c2ccccc2CN(C)C)c2cc(OC)c(OC)cc12
InChI Key InChIKey=MBGHSHPRYIPOLV-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 609384
Affinity DataIC50: 5.90nMAssay Description:Table 21: This Example illustrates that exemplary compounds of the present invention bind to SOS1 and prevent a labeled tracer ligand from occupying ...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Table 24: This Example illustrates that exemplary compounds of the present invention prevent KRas-mediated GTP nucleotide exchange mediated by SOS1 t...More data for this Ligand-Target Pair