BDBM609372 (R)N-(1-(2-methyl-3-(trifluoromethyl)phenyl)ethyl)-7-(piperazin-1-yl)pyrido[3,4-b]pyridazin-1-amine::US11702418, Example 3-1
SMILES C[C@@H](Nc1nncc2cnc(cc12)N1CCNCC1)c1cccc(c1C)C(F)(F)F
InChI Key InChIKey=ACTIBTXOTMAYDC-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 609372
Affinity DataIC50: 5.20nMAssay Description:Table 21: This Example illustrates that exemplary compounds of the present invention bind to SOS1 and prevent a labeled tracer ligand from occupying ...More data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Table 24: This Example illustrates that exemplary compounds of the present invention prevent KRas-mediated GTP nucleotide exchange mediated by SOS1 t...More data for this Ligand-Target Pair