BDBM609071 US11702418, Example 1-10
SMILES CNCc1ccccc1-c1csc(c1)[C@@H](C)Nc1nncc2ccc(cc12)N(C)C
InChI Key InChIKey=VAUGFCRDZBCPBH-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 609071
Affinity DataIC50: 2.30nMAssay Description:Table 21: This Example illustrates that exemplary compounds of the present invention bind to SOS1 and prevent a labeled tracer ligand from occupying ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Table 23: This Example illustrates that exemplary compounds of the present invention bind to SOS1 and inhibit the SOS1-mediated nucleotide exchange o...More data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Table 24: This Example illustrates that exemplary compounds of the present invention prevent KRas-mediated GTP nucleotide exchange mediated by SOS1 t...More data for this Ligand-Target Pair